Two disparate young women working for a company that conducts euthanasia are dispatched to a remote estate to perform a custom assisted-suicide ritual, but unwittingly summon the wraiths of a Death Cult that once inhabited the property.

Josh Fosse is a 20something guy whose life is going nowhere. His girl left, his rent is late, and he lacks a real job. He is trying to make it as an app reviewer online and decides to review a self help app called i-Lived for fun. He's signs on and immediately his life turns around. He meets the girl of his dreams and he gets a job offer he can't refuse. Convinced it's him and not the app, he signs out... and loses everything. He signs on again but this time the terms are different, the app is asking him to do things that are out of his moral comfort zone... but essential to becoming the success the app tells him he can be.

In the year 2056 - the not so distant future - an epidemic of organ failures devastates the planet. Out of the tragedy, a savior emerges: GeneCo, a biotech company that offers organ transplants, for a price. Those who miss their payments are scheduled for repossession and hunted by villainous Repo Men. In a world where surgery addicts are hooked on painkilling drugs and murder is sanctioned by law, a sheltered young girl searches for the cure to her own rare disease as well as information about her family's mysterious history. After being sucked into the haunting world of GeneCo, she is unable to turn back, as all of her questions will be answered at the wildly anticipated spectacular event: The Genetic Opera.